How Safe Is Vaginal Estrogen?

MedPage Today

CU’s Dr. Nanette Santoro weighs in

The American College of Obstetricians and Gynecologists (ACOG) endorsed the use of vaginal estrogen in breast cancer survivors, but CU’s Dr. Nanette Santoro urged caution in a panel on Medpage Today.

ACOG’s endorsement raised concern because vaginal estrogen contains a black box warning deterring cancer survivors from using it.

Although not authorized by the Federal Drug Administration (FDA) for use with breast cancer survivors, Dr. Santoro offered her perspective:

It’s not appropriate for a physician to turn his or her back on a patient’s suffering and tell her there’s nothing that can be done. Virtually every medication interaction involves a risk to benefit calculation. That’s what doctors are trained to provide.

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