Research, Studies & Clinical Trials

Thank you for your interest in participating in a paid research study at University of Colorado OB-GYN. All clinical trials are conducted by a physician from CU OB-GYN.

  To apply for any of the studies below, please contact Katherine Kuhn at 303-724-5276 or [email protected].

Please review all eligibility criteria to see if you would be able to participate.

Study: Menopausal Hot Flash Study

Group of diverse women in menopause trial | CU OB-GYNCurrently seeking female participants experiencing hot flashes/night sweats. Earn up to $1,000.

This double-blind study will examine the use of Granulocyte Colony-Stimulating Factor (G-CSF) to treat hot flashes, night sweats and other vasomotor symptoms (impacts on blood vessels) in women entering or currently in natural or surgical menopause. The drug being studied has previously been approved by the U.S. Food and Drug Administration (FDA) in 1991 to treat low white blood cell count. During the study, half of the women will receive a G-CSF injection while the other half will receive a placebo injection (does not contain medication).

Findings from this study may help women improve their postmenopausal symptoms in the future.

Study principal investigator: Dr. Nanette Santoro

Eligibility criteria

  • Women ages 40-65 having frequent hot flashes and/or night sweats.
  • Currently in or entering natural or surgically induced menopause.
  • No menstrual cycles for at least 12 months.
  • A BMI between 18-35. Calculate your BMI.
  • Not currently taking medications that contain hormones, or willing to stop hormone medications to participate.
  • Not currently taking SSRIs (selective serotonin reuptake inhibitors) or SNRIs (serotonin and norepinephrine reuptake inhibitors), or willing to stop taking them to participate.
  • Have had a normal Pap smear within the last two years, or willing to have a Pap smear at the screening.

To enroll all participants must meet specific criteria. Only a clinical research staff member can determine eligibility. Upon application for the study, one of our research staff members will provide the full details of the study and consent information, which will be discussed in a 10–15-minute phone pre-screening questionnaire.

Research study details

  • You will be compensated up to $1,000 for your time in the study and travel ($100 per study visit).
  • Investigational study medication or placebo at no cost.
  • Study related medical exams at no cost.
  • Your participation will include 10 outpatient study visits over 12-14 consecutive weeks and one follow-up phone call 30 days after the last visit.
  • The study visits will average 30-40 minutes with the longest lasting 1.5 hours and the shortest lasting 15 minutes.
  • This study takes place on the Anschutz Medical Campus in Aurora, CO.
  • During the study visits you will receive physicals, routine blood draws and the study medication in the form of an injection in your arm (three times over the course of study).

Study: How does the food we eat impact our reproductive hormones?

Group of diverse women in menopause trial | CU OB-GYNCurrently seeking healthy, female participants

This study aims to enhance understanding of why weight affects fertility by measuring how the foods we eat (namely high-fat foods) affect reproductive hormones. Findings from this study may help researchers understand how obese women can improve their production of reproductive hormones without extreme weight loss.

Study principal investigator: Dr. Nanette Santoro

Eligibility criteria

  • Be a healthy woman age 18-38.
  • Have a BMI between 18 and 25.
  • Have regular menstrual cycles (25-35 days).
  • Be able to eat only the foods provided by the study for one month (including dairy).
  • Not be currently using hormonal medications (like birth control medication).
  • Not be pregnant or planning to become pregnant.

To be enrolled all participants must meet specific criteria. Only a clinical research staff member can determine eligibility.

Research study details

  • You will be compensated up to $720 for your time in the study.
  • Your participation will last for approximately five menstrual cycles.
  • You will be provided with meals for one month and given a Fitbit Flex.
  • The study requires 11 clinic visits over the course of approximately six months.

  To apply for any of the studies above, please contact Katherine Kuhn at 303-724-5276 or [email protected].

Please review all eligibility criteria to see if you would be able to participate.


Study: Outcomes of Menstrual Suppression in Adolescent Females with Developmental Disabilities (COMIRB 18-2427)

  If interested in participating can call the Pediatric and Adolescent Gynecology Clinic at 720-777-2667.

The aim of the study is to prospectively follow indications, clinical characteristics, and outcomes of patients with developmental disabilities receiving menstrual suppression in the pediatric and adolescent population at Children’s Hospital Colorado. Caregivers will receive surveys at 1, 3, 6, and 12 months after patients start menstrual suppression. $10 gift cards are provided for each survey completed.